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Extra resources for Alcohol and Opiates. Neurochemical and Behavioral Mechanisms

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KLEE Wash Fig. 1. Differential effects of ethanol on resting membrane potential of Aplysia neurons. A,B: simultaneous intracellular recordings were obtained from cells L-ll (upper records) and R-15 (lower records). A: ethanol (4%) was added to the ASW at the arrow and shortly thereafter L-ll was depolarized until finally the spike generating mechanism was inactivated. In contrast, R-15 hyperpolarized and the membrane potential oscillations underlying its bursting behavior ceased. B: after 15 minutes total exposure to ethanol, the perfusion fluid was switched back to ASW at the arrow.

Biology of Alcoholism, v o l . 3 . E d i t e d by K i s s i n , B. and B e g l e i t e r , H . , Plenum P r e s s , New York, p . 1-36 ( 1 9 7 4 ) . Aurbach, A. A . : Synaptic Transmission and Neuronal Interaction. E d i t e d by B e n n e t , M. V. L . , Raven P r e s s , New York, p . 1 3 7 - 1 5 9 ( 1 9 7 4 ) . M e t c a l f e , J . C . , Seeman, P. and B u r g e n , A. S . V . : The proteon relaxation of benzyl alcohol in erythrocyte membranes. Molec. Pharmacol. -87-95 ( 1 9 6 8 ) . Seeman, P .

59. 60. 61. 62. 63. 64. 37 in vivo and in vitro in rat brain. Life. Sei. 14:22472257 (1974). Rubinstein, J. , Collins, M. A. : Inhibition of liver aldehyde dehydrogenase by pyrogallol and related compounds. Experientia 31:414-415 (1975). Collins, M. , Bigdeli, M. G. and Rubenstein, J. : Pyrogallol potentiates acetaldehyde blood levels during ethanol oxidation in rats. Chem. Biol. Interact. -127-130 (1974). Sippel, H. : The acetaldehyde content in rat brain during ethanol metabolism. J. Neurochem.

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